54527-84-3
- Product Name：Nicardipine hydrochloride
- Molecular Formula：C26H30ClN3O6
- Purity：99%
- Molecular Weight：515.994
Product Details;
CasNo： 54527-84-3
Molecular Formula： C26H30ClN3O6
Appearance： Yellow solid
Factory Sells Best Quality Nicardipine hydrochloride 54527-84-3 with GMP standards We supply high quality Nicardipine hydrochloride (CAS 54527-84-3), in stock, factory directly supply to clients, lower prices, more competitiveness.
What is the Nicardipine hydrochloride ?
Nicardipine hydrochloride is Yellow solid, while it's Molecular Formula is C26H29N3O6*ClH. Nicardipine is a dihydropyridine L-type calcium channel antagonist that displays antihypertensive and antianginal activity. It is reported to inhibit adenosine A1, A2A, and A3 receptors with Ki values of 19.6, 63.8, and 3.25 μM, respectively, and can inhibit cytochrome P450 3A4 catalytic activity with an IC50 value of 0.148 μM. Additionally, nicardipine has been shown to activate transient receptor potential A1 channels, producing an increase in Ca2+ (EC50 = 0.5 μM).
What is the CAS number for Nicardipine hydrochloride ?
The CAS number of Nicardipine hydrochloride is 54527-84-3.
More information of Nicardipine hydrochloride 54527-84-3 are:
|
Synonyms |
3,5-Pyridinedicarboxylicacid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, methyl2-[methyl(phenylmethyl)amino]ethyl ester, monohydrochloride (9CI);2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid3-[2-(N-benzyl-N-methylamino)]-ethyl ester 5-methyl ester hydrochloride;Barizin;Bionicard;Cardene;Cardene (pharmaceutical);Lecibral;Nerdipina;Nicapress;Nicardal;Nimicor;Perdipina; |
|
CAS Number |
54527-84-3 |
|
Molecular Formula |
C26H29N3O6*ClH |
|
Molecular Weight |
515.994 |
|
Melting Point |
176-178 °C |
|
Boiling Point |
603.4 °C at 760 mmHg |
|
Flash Point |
318.7 °C |
|
HS CODE |
2933399090 |
|
PSA |
113.69000 |
|
LogP |
5.33180 |
What is Nicardipine hydrochloride (54527-84-3) used for?
Nicardipine is a dihydropyridine L-type calcium channel antagonist that displays antihypertensive and antianginal activity. It is reported to inhibit adenosine A1, A2A, and A3 receptors with Ki values of 19.6, 63.8, and 3.25 μM, respectively, and can inhibit cytochrome P450 3A4 catalytic activity with an IC50 value of 0.148 μM. Additionally, nicardipine has been shown to activate transient receptor potential A1 channels, producing an increase in Ca2+ (EC50 = 0.5 μM).
InChI:InChI=1/C26H29N3O6.ClH/c1-17-22(25(30)34-4)24(20-11-8-12-21(15-20)29(32)33)23(18(2)27-17)26(31)35-14-13-28(3)16-19-9-6-5-7-10-19;/h5-12,15,24,27H,13-14,16H2,1-4H3;1H
Articles related to Nicardipine hydrochloride:
|
Article |
Source |
|
METHODS FOR TREATING CHRONIC FATIGUE SYNDROME AND MYALGIC ENCEPHALOMYELITIS |
- , (2021/03/13) |
|
Processes of manufacturing substituted-1,4-dihydropyridines, improved aqueous solutions thereof, and processes of manufacturing the solutions |
- Page/Page column 6-7, (2008/12/05) |
How to get the best price on Nicardipine hydrochloride?
Mikem (Shandong) Biopharmaceutical Science and Technology Co., Ltd. is a quality supplier and manufacturer of Nicardipine hydrochloride . You can buy high quality, low price Nicardipine hydrochloride 54527-84-3 here. Contact us.
Relevant Products
-
Manidipine hydrochlorideCAS：89226-75-5
-
CMC-Na 50MCAS：9004-32-4
-
CMC-Na 100MCAS：9004-32-4
